- Sparksville
- Settle
- Sinai
- Sparrow
- Stringtown
- Slater
- Slick Rock
- Stovall
- Sugartit
- Salt Well
- Shrout
- Slate Valley
- Stony Fork Junction
- Straight Creek
- Sidville
- Stony Point
- Sandy Furnace
- Savage Branch
- Shelby City
- Santa Fe
- South Higginsport
- Stonewall
- Stoney Point
- Sebastians Branch
- Sewell
- Shoulderblade
- Simpson
- Stevenson
- Sample
- Stinnettsville